General

• Pandemic's primary strategem is efficiency.
• Cities with three cubes should be considered a priority to prevent Outbreaks.
• Use Shuttle Flights and Charter Flights to get places quickly.
• Don't discard too many City cards of the same color if that disease has not been cured yet. Generally, more than five is too many.
• If you are the Operations Expert, concentrate on building Research Stations. These are important for both transportation and disease curing.
• The chances of drawing any given card out of the City deck are:
  • City (48 total): 81% - 84%
  • Epidemic: 7% - 10%
  • Event (5 total): 8%
• After a disease is cured, the Dispatcher and Medic make a great combation to remove disease cubes.
• Prevent the first Outbreak for as long as you can. The game gets harder once one has occurred.
• Save the "One Quiet Night" Event card for emergencies. It's the most important Event and can only be used once (unless the Contingency Planner is on the team).
• The Quarantine Specialist should be placed in a location where they can prevent outbreaks and block disease cube placement. Prioritize this over treating cities with low numbers of cubes.
• Keep an eye on the City deck. If it runs out, the game is over. You can't win Pandemic by "waiting it out".
• The Medic, Researcher, Scientist, and Dispatcher make an excellent combination of players.
  • The Medic and Dispatcher can work together at treating Outbreaks
  • The Researcher can easily give cards to the Scientist, who can cure diseases easily.